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    Genomic Selection of Canine Hip Dysplasia (CHD)

    What does genomic selection of canine hip dysplasia (CHD) mean?

    Why does the Jagdspaniel-Klub participate in a project for spaniel breeds?

    What is required for a project for the specific spaniel breeds?

    How can I support the project with my spaniel?

    Who is responsible for the project?

     

    What does genomic selection of canine hip dysplasia (CHD) mean?

    Genomic selection of CHD is a modern molecular genetic testing procedure. This new method will make it possible to predict breeding values and to select breeding mates on a reliable base. The breeding value regarding CHD is generated by genetic markers and references. Based upon the knowledge of a study regarding the German shepherd dogs, for which breed markers and references are successfully established, the methods of obtaining a more reliable prognosis can be used for all breeds.

    Why does the Jagdspaniel-Klub participate in a project for spaniel breeds?

    Once the genomic markers and references are clearly established for a breed, the breeding value regarding CHD can be defined even for puppies. The known genomic breeding value pertaining to CHD enables a more precise mating strategy and a better selection of the puppies according to their genetic disposition concerning CHD. In addition this new method allows a more reliable forecast of suffering from CHD later. The most important improvement of the new method lies in the fact that the forecast are not based upon an analysis of sibling’s data but upon the particular dog’s genomic data. In the campaign against CHD the adoption of the genomic breeding value therefore marks a big step forward.

    What is required for a project for the specific spaniel breeds?

    In order to get first results of a molecular genetic DNA testing about 200 – 300 dogs of breeds having a small population size and 300 – 500 dogs of breeds having a larger population size. 50% of the dogs should have no signs of hip dysplasia, and the other 50% should feature mild to severe CHD. Initially 50 - 100  dogs are drawn out of this random sample for a first test run, 50% each with no signs respectively mild to severe CHD. The other 200 – 400 dogs provide the basis for validation and rectification of the genomic marker's selection. The study will take 6 – 12 months after all specimen and data are available.

    How can I support the project with my spaniel?

    It is very easy to support the project. Simply join the study with a blood sample from your spaniel which has already been examined for CHD. Or simply ask your vet for a blood sample prior to the X-ray examination of your dog.

    Only three steps are required:
     

    1. See your vet

    2. Blood sample (5 ml) of your spaniel, the vet will send the specimen to the University of Veterinary Medicine Hannover.

    3. Please add a copy of the pedigree, a copy of the CHD examination results and the duly completed
     “dog information form” to the blood sample.

    That’s all!

    Who is responsible for the project?

    Contact person Jagdspaniel-Klub

    Jan Kappetijn
    Tel.: 09183-4500

     

    Contact person University of Veterinary Medicine Hannover

    Prof. Dr. Ottmar Distl
    Tel.: 0511-953-8875
    FAX: 0511-953-8582
     

    Delivery address for blood samples:

    Dr. Yvonne Marschall
    Institut für Tierzucht und Vererbungsforschung
    Stiftung Tierärztliche Hochschule Hannover
    Bünteweg 17p
    30559 Hannover
     


  Letzte Aktualisierung
       28 Dezember, 2016

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